Diagnostic Difficulties and Treatment Challenges of a Young Patient With Severe Acute Psychosis and Complete Recovery - Cureus
We present the case of a 21-year-old highly-functioning female college student of high socioeconomic background admitted with first break psychosis. Her presentation proved challenging given her unexplained hypertension, the recent history of weight loss, seemingly incidental finding of pineal gland abnormality on brain imaging, and atypical response to a second-generation antipsychotic with hypersexuality. Her clinical picture was further complicated by a history of excessive cannabis use and vaping in the months leading up to her psychosis and COVID-19 infection about a year prior to that. With strong genetic loading for schizophrenia based on family history, the working diagnosis included schizophreniform disorder with good prognostic factors. Her slow response to treatment with ultimate resolution of psychotic symptoms at the end of hospitalization challenges the initial working diagnosis of the schizophreniform disorder and portrays a likelihood of substance-induced psychosis or