Mental Health

Rykindo is a bi-weekly long-acting risperidone injection to treat patients with schizophrenia and bipolar 1 in adults. The FDA has approved Rykindo (risperidone) to treat adults with schizophrenia and as adjunctive therapy to lithium or valproate for the maintenance treatment of bipolar I disorder in adults. Developed by China-based company Luye Pharma Group, Rykindo is an extended-release injectable suspension administered via intramuscular injection once every two weeks. It was developed using Luye Pharma's microsphere technology platform. In the United States, there are about 24 million schizophrenia patients, and the estimated prevalence of schizophrenia and related psychotic disorders ranges between 0.25% and 0.64%. An estimated 4.4% of U.S. adults experience bipolar disorder at some point in their lives. Rykindo has a black-box warning about use in elderly patients. Elderly patients with dementia-related psychosis treated with antipsychotic drugs are at an increased risk of d...

Source: Mi Pham/Unsplash The prime time for developing a psychotic disorder is in the late teens to early 30s, according to the National Institutes of Health. But sometimes psychosis can develop earlier in the teens. Some public figures, such as Cecilia McGough, who leads the organization Students With Psychosis, have reported symptoms as early as childhood. So when can you expect to see symptoms, and what might you see? This is an interview with Alexander Moxam, MD, a psychiatrist at the Children's Hospital of Philadelphia's First Episode of Psychosis Program about adolescent psychosis. SM: How is adolescent psychosis different than adult psychosis? And how can parents and friends watch out for signs and symptoms? AM: The prototypical psychotic disorder, schizophrenia, as well as other psychotic disorders, are diagnosed with the same criteria, or constellation of symptoms, in adolescents as they are in adults. That being said, the already dynamic an...

The case A 17-year-old boy with a history of anxiety was transported from a juvenile detention center for altered mental status, including hallucinations and agitation. Four days prior, he had arrived at the center in his usual state of health. Upon arrival, he was placed in a solitary isolation room due to a pending coronavirus disease 2019 (COVID-19) test. Three days later he was found to be diaphoretic with visual hallucinations, paranoia (asking to change rooms, describing "snipers on the roof"), physical agitation, and bizarre behavior, including attempting to drink out of the toilet bowl. He was then taken to a community emergency department (ED), where he had a normal noncontrast head computed tomography (CT) scan. There he received lorazepam, diphenhydramine, and haloperidol, after which he became less physically agitated but remained significantly altered. He was then transferred to our tertiary care children's hospital. It was difficult to obtain an initial medi...

A dramatically different approach to transcranial magnetic stimulation is promising, but needs further study. The basic tools we have for treating depression haven't changed greatly in recent years. Medications and talk therapies are a mainstay. Lifestyle approaches, such as encouraging physical activity, sufficient sleep, and social connection, are often part of the package. If depression fails to lift, the next line of treatment for some may be a noninvasive form of brain stimulation called transcranial magnetic stimulation (TMS) that is helpful in certain cases and has very few side effects. Yet TMS requires a serious time commitment — typically a total of 36 sessions over six to nine weeks. Studies show that about a third of people who try it find that it completely relieves their depression. Recently a small, short-term study in the American Journal of Psychiatry suggested that...

There is a significantly longer time to a first recurrence of major depressive disorder (MDD) and a lower recurrence risk up to 20 years among adults with more than 3 previous episodes remitted from recurrent MDD and subsequently treated with preventive cognitive therapy (PCT), according to study findings published in Psychotherapy and Psychosomatics . Long-term study follow-ups for most psychologic interventions max-out at 6 years. The maximum follow-up period for PCT is 10 years (the DELTA study, analyzing the effectiveness of PCT as a recurrence prevention intervention among adults with recurrent MDD). Researchers sought to evaluate the effectiveness of PCT over 20 years, examining number of recurrences, percentage of depression-free time, cumulative proportion of first recurrences, time to first recurrence, and mean severity of recurrences. They conducted a follow-up of the DELTA study. Entry inclusion criteria for DELTA included adults (18 years a...

The No. 1 concern among parents? Their children's mental health, according to new polling from the Pew Research Center of 3,757 U.S. parents with children under 18.  Forty percent of parents with minor children said that they were "extremely" or "very" worried about their children struggling with anxiety or depression, and 36 percent reported feeling "somewhat" worried.  Bullying was the second highest concern, with 35 percent of parents reporting that they are "extremely" or "very" worried and 39 percent reporting that they are somewhat worried.  Mothers were more likely than fathers to express concern about most issues polled, including their children's mental health. There were also differences along race and socioeconomic status lines. While bullying was the No. 1 concern for Black parents and a close second for Asian parents, Black and Asian parents expr...

Share on Pinterest Scientists have discovered that changes in speech may be an early sign of depression. Johanna Lindberg/EyeEm/Getty Images Depression is a common mental illness that can lead to debilitating symptoms. To reach an accurate clinical diagnosis, doctors will carefully collect data on a person's symptoms, history, and presentation. Data from a recent study found that examining speech may be a critical way to help identify depression in people that have not yet been diagnosed. Further research is needed to understand how speech changes among people who are depressed. Depression is a significant mental health disorder. Accurate diagnosis ensures people get the guidance and help they need to manage their depression. Diagnosing a person with depression involves looking at various behavior changes that indicate depression. A​ recent study published in BMC Psychiatry investigated how looking at speech patterns may be useful in identifying people with depression who have no...

[unable to retrieve full-text content] Depression: Could talking more be an early sign?    Medical News Today

[unable to retrieve full-text content] The connection between Portland's recent crimes and possible mental illness    KOIN.com

Despite a few similar symptoms, bipolar disorder is not a type of personality disorder. However, it may be misdiagnosed as one, or you can have both. Bipolar disorder is considered a type of mood disorder. All types of bipolar disorder and depression are mood disorders. There are 10 types of personality disorders, but bipolar disorder is not one of them. Bipolar disorder and borderline personality disorder (BPD) are commonly confused with each other, though they're two different conditions. This confusion may happen due to: similarities in certain symptoms people receiving diagnoses of both conditions (comorbidity) misdiagnoses Mood disorders vs. personality disorders Mood disorders and personality disorders are categories of mental health conditions. Mood disorders are typically broken up into bipolar disorders and depressive disorders. These disorders are also called affective disorders because they cause significant changes in your emotional state. The following conditions are c...

Share on Pinterest Scientists have discovered that changes in speech may be an early sign of depression. Johanna Lindberg/EyeEm/Getty Images Depression is a common mental illness that can lead to debilitating symptoms. To reach an accurate clinical diagnosis, doctors will carefully collect data on a person's symptoms, history, and presentation. Data from a recent study found that examining speech may be a critical way to help identify depression in people that have not yet been diagnosed. Further research is needed to understand how speech changes among people who are depressed. Depression is a significant mental health disorder. Accurate diagnosis ensures people get the guidance and help they need to manage their depression. Diagnosing a person with depression involves looking at various behavior changes that indicate depression. A​ recent study published in BMC Psychiatry investigated how looking at speech patterns may be useful in identifying people with depression who have no...

PRESS RELEASE Published January 26, 2023 DelveInsight's, "Schizophrenia Pipeline Insight, 2023," report provides comprehensive insights about 70+ companies and 70+ pipeline drugs in Schizophrenia pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space. Key takeaways from the Schizophrenia Pipeline Insight Report DelveInsight's Schizophrenia pipeline report depicts a robust space with 70+ active players working to develop 70+ pipeline therapies for Schizophrenia treatment. The leading Schizophrenia Companies includes Forum Pharmaceuticals Inc, Amneal Pharmaceuticals, LLC, Accutest Research Laboratories (I) Pvt. Ltd., Eli Lilly and Company, Johnson & Johnson Pharmaceutical Research & Development, L.L.C, Janssen,...

Bipolar disorder is a serious mental health condition characterized by severe mood swings that are significant enough to impair daily life. The disorder affects an estimated 5.7 million U.S. adults. Once referred to as manic depression or manic depressive disorder, bipolar disorder causes episodes of mania (periods of elevated or irritable mood), hypomania and sometimes, depression. There are two types of bipolar disorder, bipolar 1 and bipolar 2, says Jasmine Kaur, M.D., a psychiatrist with Mindpath Health in San Jose, California. Here's a look at how the two types differ: Bipolar 1: Individuals with bipolar 1 disorder have experienced at least one manic episode in their lifetime (that is not due to the effects of medication, substances or medical issues). Dr. Kaur defines a manic episode as a period of "either euphoric or highly irritable mood" that persists for at least seven days. During this time, an individual may also experience symptoms such as racing thought...

An estimated 2 million times each year, people with serious mental health conditions are jailed or imprisoned in the U.S. Women are disproportionately impacted at twice the rate as men. For this population, incarceration may exacerbate pre-existing symptoms, says Carolina Estevez, Psy.D., a clinical psychologist in Miami. "Frequently, individuals who are incarcerated receive inadequate medical care and mental health treatment," says Dr. Estevez "This lack of access to proper care can result in conditions worsening over time." She adds that the stigma this population faces from staff and peers may lead to further psychological distress. In fact, 63% of incarcerated individuals who have mental health conditions do not receive treatment—and for non-white individuals, their diagnoses puts them at greater risk for solitary confinement, injury and longer sentences. The trauma and stress associated with incarceration have a potential snowball effect, exacerbating exist...

An D, Hong KS, Kim J-H. Exploratory factor analysis and confirmatory factor analysis of the Korean version of hypomania Checklist-32. Psychiatry Investig. 2011;8:334. https://doi.org/10.4306/pi.2011.8.4.334. Article  Google Scholar  Phillips ML, Kupfer DJ. Bipolar disorder diagnosis: challenges and future directions. Lancet. 2013;381:1663–71. https://doi.org/10.1016/S0140-6736(13)60989-7. Article  Google Scholar  Culpepper L. Misdiagnosis of bipolar depression in primary care practices. J Clin Psychiatry. 2014;75:e05. https://doi.org/10.4088/JCP.13019tx1c. Article  Google Scholar  McCombs JS, Ahn J, Tencer T, Shi L. The impact of unrecognized bipolar disorders among patients treated for depression with antidepressants in the fee-for-services California Medicaid (Medi-Cal) program: a 6-year retrospective...