What Is a Schizophrenic Episode? Schizophrenia is a chronic brain disorder. It is a mental illness characterized by psychosis, which is when people have trouble distinguishing between what is real and what is imagined. Symptoms of psychosis can include hallucinations, delusions, paranoia, and incoherence, says Deepak D'Souza, MD, a psychiatry professor at Yale School of Medicine. A schizophrenic episode, also known as a psychotic episode or acute schizophrenia, describes a time when the person's symptoms are particularly active, says D'Souza. Depending on the severity of the schizophrenic episode, the person may lose touch with reality, and the world can seem like a confusing jumble of sights, sounds, and information. A schizophrenic episode can last days or weeks—in rare cases, even months, says D'Souza. Some people may experience only one or two schizophrenic episodes in their lifetime, whereas for others, the episodes may come and go...