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[unable to retrieve full-text content] Efficacy and safety of aticaprant, a kappa receptor antagonist, adjunctive to oral SSRI/SNRI antidepressant in major depressive disorder: results of a phase 2 randomized, double-blind, placebo-controlled study    Nature.com
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Toxins in Wildfire Smoke May Make Their Way Into Brain - HealthDay News

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THURSDAY, Dec. 9, 2021 (HealthDay News) -- The smoke from wildfires is dangerous for your lungs, but tiny particles from the smoke can also enter your brain and cause lifelong neurological issues, a new animal study suggests. Once that happens, the particles may put people at risk for everything from premature aging and various forms of dementia to depression and even psychosis, researchers say. "These are fires that are coming through small towns and they're burning up cars and houses," said Matthew Campen, a professor at the University of New Mexico's College of Pharmacy. Campen and his team conducted research last year at Laguna Pueblo, an area 41 miles west of Albuquerque and roughly 600 miles from the source of wildfires. They found that mice exposed to smoke-laden air for nearly three weeks under closely monitored conditions showed age-related changes in their brain tissue. Microplastics and metallic particles of iron, aluminum and magnesium in wildfire smoke so...
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